Published online this week in The Journal of Allergy and Clinical Immunology, the action plan describes the proceedings from a workshop conducted in November 2019 and supported by the National Heart, Lung, and Blood Institute and the Office of Research on Women’s Health in the Office of the Director of the National Institutes of Health and the U.S. Food and Drug Administration Office of Women’s Health. The workshop assembled key stakeholders who were tasked with prioritizing, strategizing and mobilizing action steps on gaps in knowledge regarding asthma medication safety in pregnancy and lactation. The overarching goal of the workshop was to identify approaches that could be applied broadly to fill gaps in data about the safety of all medications and vaccines in pregnancy and lactation.

As a result of the workshop, a multi-stakeholder consortium on asthma medications in pregnancy and lactation has been developed. In order to address the evidence gaps and aid in populating medication labels with data that health providers can use to inform clinical decision making, the consortium developed a plan to systematically obtain necessary data in the most efficient and timely manner.  The consortium also recommended the development of guidelines for the evaluation and management of asthma during pregnancy and lactation that adhere to the standards developed by the National Academy of Medicine, which would not only offer recommendations for patients, caregivers, and health providers at the point-of-care but also highlight specific evidence gaps that warrant further research. According to Chambers, “the need for high quality information regarding medication and vaccine safety in pregnancy and lactation is great – implementation of the recommendations stemming from this workshop will be a major step forward in addressing this health disparity.”

In partnership with VAMPSS, MotherToBaby conducts observational pregnancy studies to evaluate the safety of medications used to treat asthma and other health conditions. MotherToBaby Pregnancy Studies accept both healthcare provider referrals as well as patient self-referrals. To learn more, visit: MotherToBaby.org/Studies.

Read the Abstract

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LA JOLLA, CA –A new study conducted by birth defects research experts from the non-profit Organization of Teratology Information Specialists (OTIS) launches to examine the short and long-term effects of the novel COVID-19 virus in pregnancy and breastfeeding. The observational study will consist of phone calls over the course of volunteers’ pregnancies and post-delivery, and/or breastmilk samples, as well as a release of medical records related to the pregnancy and the infant’s development.

OTIS is the scientific non-profit society that provides the no-cost MotherToBaby information service and enrolls women through the MotherToBaby Pregnancy Studies.

“Women and their health care providers need answers as quickly as possible regarding the effects of COVID-19 during pregnancy and while breastfeeding,” said the Principal Investigator, Christina Chambers, PhD, MPH, OTIS/MotherToBaby president and professor of pediatrics at UC San Diego (pictured right). “We know that pregnant and breastfeeding moms are contracting COVID-19, but the fact of the matter is that we know very little about its short and long-term effects on a developing baby,” she added. “We hope pregnant women see the importance in helping the world understand this novel virus and consider volunteering for the study.”

The study is open to pregnant and breastfeeding women in the United States and Canada with known or suspected COVID-19 infection. The MotherToBaby Pregnancy Studies Research Center is located at the University of California San Diego.

Pregnant women and breastfeeding mothers can enroll in the study at the following link https://mothertobaby.org/join-study/ or by calling MotherToBaby Pregnancy Studies at (877) 311-8972. Learn more about the ongoing observational study at https://mothertobaby.org/ongoing-study/coronavirus-covid-19/.

Health care providers can refer pregnant and breastfeeding patients with known or suspected COVID-19 infection at the following link https://mothertobaby.org/healthcare-professional-referral-form/ or by calling MotherToBaby Pregnancy Studies at (877) 311-8972.

More about OTIS and MotherToBaby

The Organization of Teratology Information Specialists (OTIS) is a professional scientific society made up of individuals engaged in assessing and evaluating risks to pregnancy and breastfeeding from environmental exposures. Members include, but are not limited to, specialists in the fields of: obstetrics and gynecology, pediatrics, genetics, dysmorphology, perinatal epidemiology, teratology, behavioral teratology, pharmacy, genetic counseling, nursing, midwifery, maternal and child health, public health, and includes experts that provide MotherToBaby services and researchers that conduct MotherToBaby Pregnancy Studies. MotherToBaby is a suggested resource by many federal agencies including the Centers for Disease Control and Prevention (CDC). To learn more about ongoing MotherToBaby Pregnancy Studies, call (877) 311-8972, email MotherToBaby@ucsd.edu or visit www.MotherToBaby.org.

The study launched March 23, 2020. Interviews with Christina Chambers, PhD, MPH are now being scheduled. Interested media, please call 619-368-3259 or email nchavez@mothertobaby.org.

The post MotherToBaby Launches First COVID-19 in Pregnancy Study appeared first on MotherToBaby.

How to participate: Follow @MotherToBaby on Facebook or @mothertobabyotis on Instagram (or both). You might get a notification from Facebook or Instagram that the MotherToBaby page you follow is going live at the live broadcast start time. Alternatively, just go to MotherToBaby’s profile on either Facebook or Instagram at the broadcast start time (10a PT/1p ET). You can also get a reminder for the live event by clicking “going” on the Facebook event created for it: https://www.facebook.com/events/213655426471361/

On Facebook, the live video should just be playing at the top of MotherToBaby’s page. On Instagram, you will see a small badge around the story circles at the top of the screen that says “live.” Tap to enter the live stream. The person streaming will know that you are tuning in.

With either platform, once you are watching the live stream, you can comment or ask questions, the same way you’d engage with a non-live post. MotherToBaby’s president, Christina Chambers, PhD will be joined by Drs. Kenneth Lyons Jones, MD and Miguel Del Campo, MD to answer questions in English and Spanish about birth defects.

The post MotherToBaby Hosts First-Ever World Birth Defects Day Facebook and Instagram Live Event March 3 appeared first on MotherToBaby.

LA JOLLA, CA –A new study conducted by birth defects experts from the Organization of Teratology Information Specialists (OTIS) suggests adalimumab use in pregnancy was not associated with an increased risk for adverse outcomes examined, such as major structural birth defects, spontaneous abortion and preterm delivery. The findings were published today in the Public Library of Science (PLOS) One Journal.

The prospective research study conducted by OTIS examined 602 pregnancies that occurred between 2004 – 2016 in women across the U.S. and Canada. Researchers enrolled pregnant women into the observational cohort study who had or had not taken adalimumab for their autoimmune disease, as well as generally healthy pregnant women for comparison. OTIS is the scientific non-profit society that provides the no-cost MotherToBaby information service and enrolls women through the MotherToBaby Pregnancy Studies Research Center at the University of California San Diego. Financial support for the adalimumab study was provided by AbbVie.

“Many women hoping to start a family rely on adalimumab to control symptoms related to crippling autoimmune diseases such as rheumatoid arthritis or Crohn’s Disease,” said lead study author Christina Chambers, PhD, MPH, OTIS/MotherToBaby president and professor of pediatrics at the University of California, San Diego. “The fact that this study showed no increased risk in adverse birth outcomes with the use of adalimumab in pregnancy is important since not a lot of research was previously available on this particular medication.”

The study also found that regardless of whether they took adalimumab or not, pregnant women with rheumatoid arthritis or Crohn’s Disease were at an increased risk of preterm birth (delivery before 37 weeks of pregnancy).

“Studies on medication use in general are lacking when it comes to understanding their effects on pregnancy, making it difficult for pregnant women and their healthcare providers to make informed decisions,” said Dr. Chambers. “We are proud to add valuable information to the literature and encourage more pregnant women to consider volunteering for critical observational studies.”

For more information on all of the current MotherToBaby Pregnancy Studies, please visit https://mothertobaby.org/pregnancy-studies/.

More about OTIS and MotherToBaby

The Organization of Teratology Information Specialists (OTIS) is a professional scientific society made up of individuals engaged in assessing and evaluating risks to pregnancy and breastfeeding from environmental exposures. Members include, but are not limited to, specialists in the fields of: obstetrics and gynecology, pediatrics, genetics, dysmorphology, perinatal epidemiology, teratology, behavioral teratology, pharmacy, genetic counseling, nursing, midwifery, maternal and child health, public health, and includes experts that provide MotherToBaby services and researchers that conduct MotherToBaby Pregnancy Studies. MotherToBaby is a suggested resource by many federal agencies including the Centers for Disease Control and Prevention (CDC). To learn more about ongoing MotherToBaby Pregnancy Studies, call (877) 311-8972, email MotherToBaby@ucsd.edu or visit www.MotherToBaby.org.

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Media Contact: Nicole Chavez, 619-368-3259, nchavez@MotherToBaby.org.

The post Study Suggests Adalimumab Exposure in Pregnancy Does Not Increase Birth Defects Risk appeared first on MotherToBaby.

OTIS, Teratology Society, SMFM, NSGC Team Up to Shed Light on Prenatal and Postnatal Marijuana Exposure Effects

BRENTWOOD, TN – From plant form to CBD oil, with increasing legalization of marijuana across U.S. states, there comes the need for more information on its impact should a consumer become pregnant. Birth defects experts from the Organization of Teratology Information Specialists (OTIS), the scientific non-profit society that provides the MotherToBaby no-cost service, are offering the latest data surrounding marijuana exposure in pregnancy and lactation during a free webinar for healthcare providers on May 2, 2019 at 12p Pacific/3p Eastern.

“If I use edibles instead of smoke marijuana, that should be safer during pregnancy and breastfeeding, right?” – It’s just one of the many questions the MotherToBaby service, which answers questions about exposures during pregnancy and breastfeeding via phone, text, live chat and its MotherToBaby.org website, is now receiving on a regular basis according to Christina Chambers, PhD, MPH, MotherToBaby president and professor of pediatrics at the University of California, San Diego. Dr. Chambers also heads up Mommy’s Milk Human Milk Research Biorepository, the first-ever research database of human breast milk which produced a ground-breaking study last year suggesting that marijuana can linger in breast milk for far longer (up to six days) than previously thought. “As more states legalize marijuana for medicinal and recreational use, it’s critical we look at how it’s impacting the next generation,” she said.

The webinar, “Sifting through the Smoke: The Latest Research Surrounding Marijuana Exposure in Pregnancy and Breastfeeding,” is a collaboration with the National Society of Genetic Counselors (NSGC) and, in addition to OTIS/MotherToBaby, will include presenters representing the Teratology Society and the Society for Maternal-Fetal Medicine (SMFM). The webinar is free and aimed at healthcare providers and researchers; registration is required at the following link: http://bit.ly/MarijuanaWebinar2019.

“Older studies have suggested that if a mother uses marijuana during pregnancy, she might be at risk for having a smaller baby born early and/or having it experience developmental delays,” said Sarah Obican, MD, a Maternal-Fetal Medicine subspecialist at the University of South Florida, director of MotherToBaby’s Florida affiliate, and Dr. Chambers’ co-presenter for the webinar. “However, marijuana is produced today at a higher potency level, so it’s critical we stay vigilant in our research to better understand its impact,” she added.

The webinar is expected to run approximately one hour and presenters will be available to answer questions from attendees.

More about OTIS and MotherToBaby

The Organization of Teratology Information Specialists (OTIS) is a professional scientific society made up of individuals engaged in assessing and evaluating risks to pregnancy and breastfeeding from environmental exposures. Members include, but are not limited to, specialists in the fields of: obstetrics and gynecology, pediatrics, genetics, dysmorphology, perinatal epidemiology, teratology, behavioral teratology, pharmacy, genetic counseling, nursing, midwifery, maternal and child health, public health, and includes experts that provide MotherToBaby services and researchers that conduct MotherToBaby Pregnancy Studies. MotherToBaby is a suggested resource by many federal agencies including the Centers for Disease Control and Prevention (CDC). To be connected with a MotherToBaby expert, please call (866) 626-6847, text questions to (855) 999-3525 (standard messaging rates might apply, check with your carrier) or visit www.MotherToBaby.org.

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Media Contact: Nicole Chavez, 619-368-3259, nchavez@MotherToBaby.org.

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The post In Case You Missed It – Recorded MotherToBaby Pregnancy Registry Two-Part Webinar Series appeared first on MotherToBaby.

FOR IMMEDIATE RELEASE
January 8, 2019

BRENTWOOD, TN – “A baby is born with a birth defect in the United States every 4 ½ minutes. We can change that alarming statistic,” said Christina Chambers, PhD, MPH, President of MotherToBaby, a free service of the non-profit Organization of Teratology Information Specialists (OTIS). MotherToBaby is joining with leading prenatal health experts from the National Birth Defects Prevention Network (NBDPN), Centers for Disease Control and Prevention (CDC), American Academy of Pediatrics, the March of Dimes, and the Teratology Society this month to increase awareness of 5 critical tips to reduce the chances of having a baby with a birth defect.

The National Birth Defects Prevention Month campaign theme, “Best for You. Best for Baby.” aims to raise awareness of preventable birth defects. “Furthermore, we want to emphasize the importance of pregnancy registries, which often lead to the discovery of even more ways to prevent birth defects,” explained Dr. Chambers, who also serves as professor of pediatrics at UC San Diego. MotherToBaby will join the Teratology Society and the Society for Maternal-Fetal Medicine in co-hosting a free two-part webinar series for healthcare providers on the importance of pregnancy exposure research, its challenges and the new Task Force on Research Specific to Pregnant and Lactating Women (PRGLAC) report. The webinar series will take place Thursday January 17th at 1pm-1:30 ET and Tuesday January 29th at 12pm-12:30p ET and will be free to join, but advanced registration is required at the following links:

• Current and Future Trends in Research with Pregnant and Lactating Women (Part 1): http://bit.ly/PregResearch1
• Using Registries and Crowdsourcing to Conduct Research with Pregnant and Lactating Women (Part 2):
  http://bit.ly/PregResearch2

MotherToBaby provides free evidence-based information to mothers, health care professionals, and the general public about medications and other exposures during pregnancy and while breastfeeding through its helpline (866) 626-6847, texting service (855) 999-3525, or via live chat and email on www.MotherToBaby.org. MotherToBaby also has a free app available for iOS and Android devices. MotherToBaby is recommended by many agencies, including the CDC.

MotherToBaby encourages the public to follow these steps to increase chances of a having a healthy baby:

1. Be sure to take 400 micrograms (mcg) of folic acid every day.
   • Folic acid is very important because it can help prevent some major birth defects of the baby’s brain and spine.
2. Book a visit with your healthcare provider before stopping or starting any medicine.
   • There are often benefits to continuing treatment throughout pregnancy. Discussing a treatment plan before a pregnancy allows a woman and her health care provider to weigh the pros and cons of all options to keep mom and baby as healthy as possible.
3. Become up-to-date with all vaccines, including the flu shot.
   • Having the right vaccinations, like the flu and Tdap vaccines, at the right time during pregnancy can help keep a woman and her baby healthy.
4. Before you get pregnant, try to reach a healthy weight.
   • Obesity increases the risk for several serious birth defects and other pregnancy complications.
5. Boost your health by avoiding harmful substances during pregnancy, such as alcohol, tobacco, and other drugs.
   • There is no known safe amount of alcohol during pregnancy and its exposure can cause major birth defects.
   • Smoking during pregnancy can cause dangerous chemicals to damage the placenta and/or reach baby’s bloodstream.
   • The opioid addiction epidemic has led to a sharp increase in Neonatal Abstinence Syndrome (NAS), premature birth and drug withdrawal in developing babies.

“Birth defects are a common cause of death in the first year of a baby’s life, but change happens through awareness,” added Jason L. Salemi, PhD, MPH, NBDPN President. “We’re thrilled MotherToBaby is doing its part to positively change the outcome for babies across North America.”

How You Can Help

MotherToBaby encourages health advocates as well as the general public to be active participants in National Birth Defects Prevention Month. Follow and share #Best4YouBest4Baby messages on social media platforms, such as Facebook, Twitter, Instagram and LinkedIn. In addition, the complete 2019 NBDPN Birth Defects Prevention Month information packet, including this year’s primary tips for birth defects prevention, “Best for You. Best for Baby. 5 Tips for Preventing Birth Defects,” is available online at: https://www.nbdpn.org/bdpm.php. All materials can be printed, electronically conveyed, or added to websites for distribution as needed.

Additional Resources to Support Healthy Pregnancies

Centers for Disease Control and Prevention
The CDC’s National Center on Birth Defects and Developmental Disabilities (NCBDDD) strives to advance the health and well-being of our nation’s most vulnerable populations.
www.CDC.gov/ncbddd

American Academy of Pediatrics
Dedicated to the health of all children, providing age-specific health information.
www.healthychildren.org

The Teratology Society
An international and multidisciplinary group of scientists including researchers, clinicians, epidemiologists, and public health professionals from academia, government and industry who study birth defects, reproduction, and disorders of developmental origin.
www.Teratology.org

March of Dimes
An organization aiming to make sure babies get the strongest start possible as well as reducing the rate of prematurity.
www.marchofdimes.org

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Media Contact: Nicole Chavez, 619-368-3259, nchavez@MotherToBaby.org. Interviews in Spanish are also available.

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